Ivermectin Protocol Guide
Last updated: March 2026
Weight-based dosing, research overview, and combination protocols
🏥 About Ivermectin
Ivermectin is a Nobel Prize-winning medication originally developed as an antiparasitic drug. Recent research has identified potential anti-cancer, anti-viral, and anti-inflammatory properties that extend beyond its original use.
Safety Profile: Ivermectin has been used safely in humans for decades, with over 4 billion doses administered worldwide for parasitic infections.
⚖️ Weight-Based Dosing
Ivermectin dosing is based on body weight. Standard protocols range from 0.2mg to 0.4mg per kilogram of body weight.
| Body Weight (lbs) | Body Weight (kg) | 0.2mg/kg Dose | 0.4mg/kg Dose |
|---|---|---|---|
| 110-130 | 50-59 | 10-12mg | 20-24mg |
| 130-150 | 60-68 | 12-14mg | 24-27mg |
| 150-170 | 68-77 | 14-15mg | 27-31mg |
| 170-190 | 77-86 | 15-17mg | 31-34mg |
| 190-210 | 86-95 | 17-19mg | 34-38mg |
| 210-230 | 95-104 | 19-21mg | 38-42mg |
| 230-250 | 104-113 | 21-23mg | 42-45mg |
Important: Start with lower doses and assess tolerance. Take with food for better absorption and reduced potential for stomach upset.
📋 Protocol Options
Different protocols have emerged based on various applications and research:
🔬 Mechanisms of Action
Research has identified multiple pathways through which ivermectin may exert beneficial effects:
- Multi-Target Activity: Acts on multiple cellular pathways simultaneously
- P-glycoprotein Inhibition: May help overcome drug resistance in cancer cells
- PAK1 Pathway Blocking: Inhibits pathways involved in cancer cell growth and survival
- Anti-Angiogenic Effects: May prevent formation of new blood vessels feeding tumors
- Immunomodulation: May help regulate immune system responses
- Autophagy Induction: May trigger cellular cleanup mechanisms
📚 Research Overview
Emerging research suggests ivermectin may have applications beyond its original antiparasitic use:
Anti-Cancer Research
Additional Research Areas
- Breast Cancer: Studies show potential in triple-negative breast cancer
- Ovarian Cancer: Research on drug-resistant ovarian cancer cells
- Glioblastoma: Studies on brain cancer applications
- Leukemia: Research on blood cancer cell lines
Research Status: Most studies are preclinical (laboratory and animal models). Human clinical trials are limited but emerging.
🔗 Combination Protocols
Some protocols combine ivermectin with other compounds for potentially enhanced effects:
Ivermectin + Fenbendazole
Approach: Alternate the compounds or use them on different schedules
- Ivermectin: 0.3mg/kg twice weekly
- Fenbendazole: 222mg, 3 days on/4 days off (Joe Tippens Protocol)
- Supporting supplements: Vitamin E, CBD, Curcumin
Note: Some people use both simultaneously, others alternate weekly. Monitor for any adverse effects.
Enhanced Support Stack
Additional supplements often used with ivermectin:
- Zinc: 30-50mg daily (immune support)
- Vitamin D3: 2000-5000 IU daily
- Quercetin: 500mg daily (zinc ionophore)
- NAC: 600mg daily (glutathione support)
🛒 Where to Buy
Quality and purity are essential. Here are options for obtaining ivermectin:
Human-grade tablets from pharmacy
Requires physician prescription
Pros: Precise dosing, human-grade
Horse dewormer (1.87% ivermectin)
Calculate dose based on weight
Buy on Amazon →Human-grade tablets available
Various online sources
Note: Research legality in your area
Dosing Calculation: For horse paste (1.87%), each gram contains 18.7mg ivermectin. For a 70kg person needing 21mg (0.3mg/kg), that equals approximately 1.1 grams of paste.
⚠️ Safety Considerations
- Start Low: Begin with lower doses to assess tolerance
- Food Timing: Take with food to improve absorption and reduce stomach upset
- Drug Interactions: May interact with blood thinners and other medications
- Pregnancy/Nursing: Not recommended during pregnancy or breastfeeding
- Liver/Kidney Issues: Use caution with compromised liver or kidney function
Side Effects: Generally well-tolerated. Possible effects include nausea, diarrhea, dizziness, or fatigue. Most are mild and temporary.
🔬 Related Research
- Ivermectin & Glioblastoma: What the Research Shows — Comprehensive review of preclinical studies on ivermectin's anti-tumor effects in brain cancer, including Akt/mTOR inhibition, mitochondrial dysfunction, and autophagy induction.
⚠️ Important Medical Disclaimer
This is educational content for research purposes only, not medical advice. Ivermectin protocols discussed here are experimental and not approved by the FDA for cancer treatment. This information is provided for educational and research purposes based on emerging studies and anecdotal reports. Always consult with qualified healthcare professionals before making any health decisions. Individual results may vary and this information should not replace professional medical care.