๐ Recently Added New
Newest and recently-rewritten pages across the full research library.
S4 (Andarine) Guide
Partial AR agonist cutting SARM โ known for yellow vision side effect at high doses.
SR-9009 (Stenabolic) Guide
Rev-Erbฮฑ agonist exercise mimetic โ +50% endurance in mice. Poor oral bioavailability.
ACP-105 Guide
Mild partial SARM โ lower binding affinity, potentially fewer side effects than RAD/LGD.
LGD-3303 Guide
Potent full AR agonist SARM โ more suppressive than LGD-4033. Advanced compound.
AC-262,536 Guide
Partial AR agonist โ 66% anabolic / 27% androgenic ratio. Milder SARM option.
RAD-150 (TLB-150) Guide
Esterified RAD-140 โ benzoate ester extends half-life and stability.
GW-0742 Guide
Selective PPARฮด agonist โ next-gen cardarine for endurance and fat oxidation.
GHRP-2 Research
Hexapeptide GH secretagogue โ 100-300mcg 2-3x daily, ~7.5x GH peak. Compared with GHRP-6 and Ipamorelin.
Low-Dose Naltrexone (LDN)
Off-label 1-4.5mg protocol. Endorphin upregulation, TLR4 modulation, autoimmune applications.
Lion's Mane Mushroom
NGF and BDNF support, cognitive function research, nerve-regeneration studies.
Thiamine B1 Mega-Dose Protocol
High-dose B1 for neurodegeneration and brain health โ Costantini protocol with clinical citations.
L-Tyrosine Research
Dopamine precursor โ military-tested cognitive performance under stress, dosing and timing.
Dapoxetine (Priligy)
On-demand SSRI for premature ejaculation. 30-60mg 1-3hr pre-activity, efficacy vs alternatives.
Ceylon Cinnamon
The safe blood sugar spice โ Ceylon vs Cassia coumarin, glucose data, daily supplementation safety.
SR-9011 Research
Rev-Erbฮฑ agonist โ exercise mimetic, metabolic research, compared with Cardarine and MK-677.
Ancient Psychedelic Protocols
Historical and modern psychedelic protocols โ cultural, pharmacological, contemporary research.
GLP-1 & Muscle Loss
How GLP-1 weight loss affects lean mass, mitigation protocols, and what the trials show about sarcopenia risk.
Epitalon (AEDG): Deep Research Dive
Khavinson's tetrapeptide. Telomerase activation, pineal gland regulation, 25+ years of Russian longevity research.
Myo-Inositol: PCOS & Fertility
40:1 myo:D-chiro ratio, 4g/day. Matches metformin for PCOS insulin sensitivity with far fewer side effects. Strong fertility + IVF data.
Modafinil: Wakefulness & Cognition
Eugeroic for narcolepsy and shift-work. Strongest cognitive effects in sleep-deprived states; Limitless-narrative oversold for rested users.
Gut Healing Stack
BPC-157 alone isn't enough โ a 4-pathway protocol with KPV, L-glutamine, zinc-carnosine, butyrate, curcumin.
Ebook
The Complete Peptide Protocol Guide
47-page guide: protocols, dosing, sourcing — everything in one place.
Get the guide — $19 (normally $29) → New to peptides? Start with the $19 Buyer’s Playbook → All ebooks & guides →๐ GLP-1 & Weight Loss Peptides Clinical Trials
Breakdowns of landmark clinical trials for FDA-tracked weight loss peptides
Semaglutide & Cartilage Repair
17% cartilage thickness gain in 24 weeks via a weight-independent GLP-1R-AMPK-PFKFB3 pathway.
How to Get Retatrutide
Sourcing guide for the GLP-1/GIP/glucagon triple agonist - compounding, research vendors, trials, and red flags.
Retatrutide Research Results
Phase 2 trial: 24.2% weight loss in 48 weeks โ the triple agonist data visualized. Now with Phase 3 cross-links.
Retatrutide: 28% vs 18%
Why retatrutide is 55% more effective than semaglutide โ not "slightly better." Triple receptor agonist comparison.
Retatrutide Before & After
Clinical weight loss results by week, by dose. Real data โ not anecdotes.
Retatrutide Side Effects
Complete Phase 2 safety data (N=338). GI rates by dose, severity, and comparisons.
Retatrutide Weight Loss Protocol
Next-gen triple agonist (GLP-1/GIP/glucagon). Up to 24% body weight loss in trials. Dosing, timeline, and safety.
GLP-1s & Insulin Resistance
How GLP-1 agonists improve metabolic health BEFORE weight loss. Acanthosis nigricans, beta cell protection, food noise.
GLP-1 Pipeline: What's Coming Next
5 next-gen weight loss drugs: orforglipron (oral), cagrisema, survodutide, pemvidutide, mazdutide. 20%+ weight loss, dual agonists.
Liraglutide & Dulaglutide Comparison
The original GLP-1 agonists compared: daily vs weekly, SCALE/LEADER vs AWARD/REWIND trials, 8% vs 4% weight loss, when older GLP-1s are still the right choice.
Oral vs Injectable Peptides
Why most peptides must be injected. The semaglutide pill exception. Which ultra-short peptides survive digestion.
Tirzepatide Research Results
SURMOUNT-1 trial: up to 20.9% weight loss. Mounjaro/Zepbound data breakdown.
Semaglutide Research Results
STEP 1 clinical trial: 14.9% average weight loss over 68 weeks. Ozempic/Wegovy data.
Tirzepatide vs Semaglutide
Dual GIP/GLP-1 vs GLP-1 only. SURMOUNT vs STEP: 22.5% vs 15.8% weight loss, A1C, dosing, cost compared.
Ozempic Alternatives (2026 Guide)
Every Ozempic alternative compared โ tirzepatide, retatrutide, compounded semaglutide, oral GLP-1s, and natural options.
Semaglutide Not Working? 8 Reasons
Why your semaglutide stopped working โ dose issues, metabolic adaptation, diet drift โ and evidence-based fixes.
Best Peptides for Weight Loss
6 weight loss peptides ranked by evidence: semaglutide, tirzepatide, retatrutide, tesamorelin, CJC/Ipa, AOD-9604.
Best Peptides for Anti-Aging
Longevity peptides ranked and routed to deep guides: epitalon, NAD+, MOTS-c, humanin, thymalin, FOXO4-DRI.
Best Peptides for Skin & Hair
Skin and hair peptides ranked โ GHK-Cu leads โ plus BPC-157, the skin-aging stack, thymalin, and epitalon.
Best Peptides for Sleep
Sleep peptides and protocols ranked โ DSIP leads โ plus epitalon and our sleep-optimization playbooks.
๐ฉน Healing & Recovery Peptides Research
What the published literature actually says about healing peptides
Jay Campbell Healing Stack
10-compound tissue regeneration protocol: GLOW blend, bioregulators, gut restoration, immune activation.
Recovery Peptide Stacks
BPC-157 + TB-500, GHK-Cu combos, and full recovery protocols. Dosing schedules, synergy mechanisms, and monthly cost breakdowns.
KLOW Blend Research
The 4-peptide recovery stack: GHK-Cu + KPV + BPC-157 + TB-500. Synergistic repair pathways visualized.
BPC-157 Research
What 544 studies actually show about healing, gut protection, and musculoskeletal repair.
BPC-157 for Knee Pain
Human study: 11/12 patients got significant relief from a single injection lasting 6-12 months.
BPC-157 for Back Pain
Spinal cord injury recovery, neuroprotection for sciatica, and disc healing mechanisms โ research breakdown.
BPC-157 for Shoulder Pain
Rotator cuff recovery in animal models, tendon healing mechanisms, and extrapolation from knee study data.
Pentadeca Arginate (PDA)
Modified BPC-157 built for oral delivery. Why it's trending post-FDA crackdown, evidence review, and honest dosing guidance.
TB-500 Research
Thymosin Beta-4: 544+ studies on tissue repair, inflammation, and recovery โ honest assessment.
GHK-Cu: Topical vs Injectable
72 biological actions, 4,000+ genes. Copper tripeptide delivery comparison โ proven topical vs controversial injectable.
Peptide Quality & Testing
The Janoshik standard, LCMS testing, purity explained, CoA reading guide, and heavy metals myth-busting.
BPC-157 vs TB-500
Two healing peptides compared: gut/tendon repair vs systemic tissue recovery. Mechanisms, dosing, stacking, and research status.
TB-500 vs Full Thymosin Beta-4
Fragment vs complete peptide โ does TB-500 deliver the same results as full TB4? Mechanisms, clinical evidence, and when the complete protein matters.
Peptide Sciences Shut Down: What Now?
Peptide Sciences closed March 6, 2026. The FDA reclassified 14 peptides to Category 1. Your complete guide to the two paths forward.
Best Peptides for Joint Pain
BPC-157, TB-500, GHK-Cu ranked by evidence strength. Mechanisms, dosing, and combination protocols.
KPV Peptide Research
The 3-amino acid anti-inflammatory tripeptide. Oral bioavailability, gut healing, and NF-ฮบB inhibition.
LL-37 Antimicrobial Peptide
Human cathelicidin โ innate immune defense. Antimicrobial, wound healing, biofilm disruption.
BPC-157 Delivery Methods
Injection vs oral vs nasal spray โ bioavailability comparison, when to use each route, and practical dosing.
BPC-157 Oral for Gut Healing
Complete guide to oral BPC-157 for IBS, IBD, leaky gut, ulcers, gastritis, and GERD. Dosing and protocols.
BPC-157 Safety & Cancer Risk
Honest assessment of angiogenesis risks, cancer considerations, and what the research actually shows about long-term use.
BPC-157 + TB-500 for Arthritis
Combination protocol for joint pain and arthritis. Dosing, injection sites, stacking schedule, and expected timeline.
๐ Growth Hormone Peptides Research
GHRH analogs, GH secretagogues, and growth hormone optimization research
PEG-MGF Guide
PEGylated Mechano Growth Factor โ an IGF-1 splice variant that activates muscle satellite cells for repair.
IGF-1 LR3 Guide
Long-acting IGF-1 analog โ Arg3 substitution triples half-life to ~20hr, drives muscle hyperplasia.
IGF-1 DES Guide
Truncated IGF-1 (des(1-3)IGF-1) with 10x receptor potency and localized intramuscular anabolic effect.
Sermorelin: Complete GHRH Guide
GHRH (1-29) analog: pulsatile GH release, IGF-1 data, sleep effects, and comparisons vs HGH, ipamorelin, CJC-1295, tesamorelin.
HGH (Somatropin) Guide
FDA-approved since 1985. $500-3000/mo cost, 1-2 IU anti-aging dose, risks include insulin resistance and joint pain.
MK-677 (Ibutamoren) Guide
Oral GH secretagogue (not a peptide). ~40% IGF-1 increase, 10-25mg daily, 24hr half-life.
GHRP-6 Research
Strongest appetite stimulation of all GHRPs. Used for wasting conditions. ~6x GH increase.
Tesamorelin Guide
FDA-approved GHRH analog for visceral fat loss and anti-aging. GH release, body composition data, and clinical protocols.
CJC-1295 + Ipamorelin Stack
The most popular GH secretagogue stack. GHRH analog + selective GHRP = amplified GH pulse. Teichman 2006 DAC data, Raun 1998 selectivity, dosing protocols.
Hexarelin Research
Most potent synthetic GHRP. Unique CD36 cardioprotection. Produces largest GH pulses but elevates cortisol/prolactin. 2-4 week cycle only.
GH Secretagogues Comparison
Hexarelin vs GHRP-2 vs GHRP-6 vs Ipamorelin: complete comparison of ghrelin receptor agonists. GH pulse data, selectivity, side effects, dosing protocols.
โ๏ธ Hormones & Growth Hormone Axis Research
Testosterone optimization, hormone replacement, and endocrine research โ from DHEA to estradiol
Trinity Stack: Test + GH + Reta
Testosterone, growth hormone, and retatrutide combined for brain-first cognitive gains and body recomp.
DHEA: Benefits & Research
Dehydroepiandrosterone โ declines 80% by age 70. 25-50mg dosing, OTC since 1994.
HCG: Uses & Protocols
Fertility and TRT adjunct. 250-500 IU 2x weekly. FDA compounding changed in 2020.
Enclomiphene Research
SERM for testosterone โ raises T ~175% without shutdown. 12.5-25mg oral.
Estradiol & Progesterone HRT
0.5-2mg estradiol, 100-200mg progesterone. WHI study context and current guidelines.
Testosterone Bloodwork Guide
What to test, how to read your results, and why "normal" isn't the same as optimal. Complete panel guide.
Testosterone & TRT Guide
Complete testosterone research โ from diagnosis to protocols. TRT, enclomiphene, HCG, and more.
TRT Complete Guide
Everything about testosterone replacement therapy โ protocols, bloodwork, side effects, and results.
PCT: Post-Cycle Therapy Guide
Essential after any suppressive SARM or hormone cycle. HPG axis recovery, SERM protocols, bloodwork guide.
TRT vs Enclomiphene vs HCG
Head-to-head comparison of the 3 testosterone treatment paths โ T levels, fertility, cost, and reversibility.
Aromatase Inhibitor Guide
Estrogen management on TRT โ when you need an AI, when you don't, and how not to crash your E2.
TRT + Peptides Stack Guide
The complete biohacker stack โ CJC/Ipa, BPC-157, HCG, MK-677, GHK-Cu. Protocols, bloodwork, and costs.
Oxytocin Guide
Therapeutic uses, nasal spray vs injection dosing, social bonding, and clinical research on the "love hormone."
PT-141 (Bremelanotide) Guide
FDA-approved melanocortin receptor agonist for HSDD. Phase III clinical data, mechanism review, and dosing protocols.
โณ Bioregulators & Longevity Peptides Research
Khavinson bioregulators and anti-aging peptide research โ 40+ years of data
Vilon Guide
Khavinson thymus dipeptide (Lys-Glu) โ modulates immune cells and inhibited tumor growth in mice.
Testagen: Testicular Bioregulator
Khavinson bioregulator peptide isolated from testicular tissue, studied for Leydig cell support and steroidogenesis.
Bronchogen Guide
Khavinson respiratory tetrapeptide (AEDL) studied for bronchodilating and anti-inflammatory effects.
Complete Bioregulators Guide
All 11 Khavinson bioregulators: dosing, stacking protocols, cycling guide, and oral bioavailability.
Pinealon (EDR) Research
Neuroprotection tripeptide. 72 TBI patients, 59.4% memory improvement, sleep architecture optimization.
Pinealon: Sleep & Neuroprotection Guide
BBB-crossing tripeptide guide: serotonin/melatonin modulation, Khavinson family context, dosing protocols, and who it's for.
Russian Longevity Stack
The complete Khavinson protocol: Epitalon + Pinealon + Vilon + Vesugen stacking and cycling guide.
Pinealon + Epitalon Synergy Stack
The Russian longevity duo โ neuroprotection + telomere maintenance + circadian optimization in one pulsed protocol.
Thymosin Alpha 1 (TA1)
28-amino-acid thymic peptide. Approved as Zadaxin in 30+ countries. Enhances T cells, NK cells, dendritic function, and unmasks senescent cells.
๐งฌ Mitochondrial Peptides Research
Peptides derived from mitochondrial DNA โ research on cellular energy, aging, and metabolic health
SLU-PP-332: Exercise Mimetic
ERRalpha/gamma agonist that boosts running endurance and oxidative muscle fibers in mice. Animal data only, no human trials.
Humanin: Neuroprotective MDP
First mitochondrial-derived peptide (2001). Anti-apoptotic, neuroprotective, declines 40% with age. Alzheimer's and metabolic syndrome research.
Humanin Research (Overview)
24-amino acid peptide from mtDNA. Cytoprotective, anti-apoptotic, insulin-sensitizing. Research in Alzheimer's, diabetes, cardiovascular.
MOTS-c: Exercise Mimetic MDP
16-amino acid mtDNA-encoded peptide. Activates AMPK, promotes metabolic homeostasis, enhances exercise capacity. Levels decline ~50% with age.
SS-31 (Elamipretide) Guide
Tetrapeptide targeting cardiolipin. Phase 3 trials for Barth syndrome, heart failure, AMD. Larimar Therapeutics.
SS-31 Elamipretide: Clinical Trial Data
Deep-dive: Phase 2/3 results, cardiolipin-binding mechanism, pharma pipeline story, safety profile, and mitochondrial dysfunction context.
Mitochondrial Energy Stack
Three-layer energy system: NAD+ (fuel), MOTS-c (biogenesis signal), 5-Amino-1MQ (NAD+ preserver). Fix the engine, not the gas pedal.
๐ง Nootropics & Cognitive Enhancement Guides
Research-backed guides to cognitive enhancement โ from foundation compounds to advanced protocols
Semax Guide
Russian ACTH(4-10) analog nootropic that upregulates BDNF 1.4-fold; approved in Russia for stroke and cognition.
Selank Guide
Russian synthetic heptapeptide anxiolytic that modulates GABA receptors without sedation or dependence.
Pramiracetam Guide
Fat-soluble racetam ~15-30x stronger than piracetam. Enhances hippocampal choline uptake (HACU) for memory.
Pramipexole Guide
FDA-approved D2/D3 dopamine agonist used off-label for anhedonia and treatment-resistant depression.
Phenibut Guide
Soviet GABA-B agonist anxiolytic and sleep aid with high addiction risk - tolerance builds in days.
Oxiracetam Guide
Water-soluble AMPA/NMDA racetam with a mild stimulant edge for logic, attention, and focus. 400-800mg dosing.
NSI-189 Guide
Neurogenic small molecule that increased hippocampal volume ~2.4% in a Phase 2 depression trial.
Nootropics Research Hub
Cognitive-enhancement hub: racetams, peptide nootropics, adaptogens, cholinergics, and stimulants with evidence ratings.
Fasoracetam Guide
Racetam nootropic that upregulates GABA-B receptors and modulates mGluR; the only racetam with ADHD trial data.
DSIP Guide
Endogenous 9-amino-acid sleep peptide that promotes delta-wave sleep, modulates cortisol, and shows analgesic effects.
Coluracetam Guide
Visual-enhancing racetam (MKC-231) that potently upregulates HACU; only racetam with MDD trial data.
Cerebrolysin Guide
Porcine brain-derived peptide mixture with 200+ clinical studies, approved in 40+ countries for stroke, TBI, dementia.
TTFD (Allithiamine) Guide
Lipophilic thiamine for gut/autonomic support, POTS, and heavy metal chelation. Paradox reaction guide and cofactor protocol.
Sulbutiamine Guide
The only dopaminergic thiamine โ upregulates D1 receptors for motivation and cognition. Cycling protocol required.
Complete Nootropic Stack Guide
3-tier protocol: Foundation โ Optimization โ Advanced. 10 compounds, cycling calendar, interaction warnings.
Anti-Dementia & Neuroprotection Stack
10-compound protocol for cognitive preservation: thiamine, lion's mane, bacopa, alpha-GPC, omega-3, CDP-choline, NAC, methylene blue, CoQ10, bromantane.
Modafinil: The Complete Guide
FDA uses, cognitive enhancement research, mechanism, dosing, and military studies.
Bromantane Research
Soviet actoprotector: dual dopamine + serotonin synthesis. The "want to work" drug. WADA banned 1996.
Meldonium (Mildronate) Research
Latvian carnitine inhibitor: shifts cells to oxygen-efficient glucose metabolism. Caught Sharapova. WADA banned 2016.
Benfotiamine Research
Fat-soluble B1 with 5-11x better absorption. Clinical trials on neuropathy, AGE reduction, and Alzheimer's.
Racetam Guide
Aniracetam, oxiracetam, pramiracetam, phenylpiracetam, and omberacetam compared.
CDP Choline (Citicoline)
Mandatory modafinil cofactor. Acetylcholine precursor + uridine source. CDP vs Alpha-GPC comparison.
L-Theanine Research
Alpha wave promoter. Calm focus without sedation. The perfect stimulant companion โ 200mg = 8 cups green tea.
Tadalafil for Cognition
Low-dose PDE5 inhibitor as cognitive enhancer. +15-25% cerebral blood flow. Stimulant vasoconstriction fix.
NAC: The Nightly Reset
Glutathione precursor. Neuroprotection, addiction studies, liver guardian. Take before bed, never with stims.
Semax Research
Russian ACTH(4-10) analog. Upregulates BDNF 1.4x and NGF 2x. Approved in Russia for stroke recovery and cognitive impairment. Mechanism, clinical evidence, dosing, and Selank comparison.
Cerebrolysin Research
Porcine brain-derived neuropeptide mixture. 200+ clinical studies. Approved in 40+ countries for stroke, TBI, and dementia. BDNF/NGF mimetic effects.
Selank Research
Russian anxiolytic neuropeptide (tuftsin analog). GABA-A allosteric modulation. Comparable to benzodiazepines without sedation or dependence. Approved Russia 2009. Dosing, mechanism, clinical evidence.
DSIP (Delta Sleep-Inducing Peptide)
9-amino acid neuropeptide for deep sleep. Promotes delta-wave sleep, modulates stress response and pain. Pairs well with Selank. Research, protocols, and safety.
Flow State Stack
Nootropic stacking for sustained flow states. Compounds, timing, and the neuroscience of deep work.
NAD+ Research Guide
Clinical trial data on NMN, NR, and NAD+. What the science supports โ and what it doesn't.
Methylene Blue Guide
140-year-old drug reimagined as a nootropic. Mechanisms, neuroprotection, dosing, and the blue tongue test.
What Huberman Said About Peptides
Complete breakdown of both Huberman Lab peptide episodes โ BPC-157, GH secretagogues, GLP-1s, and risks.
Dihexa: HGF/c-Met Activator
Synaptogenesis peptide with extraordinary in vitro potency. HGF/c-Met pathway, animal data only, fosgonimeton Phase 2 connection, cancer risk analysis.
Dihexa Research Guide
Hexapeptide 10Mร BDNF potency. HGF/c-Met activator. Very limited research โ high uncertainty.
Noopept Research Guide
Russian cognitive enhancer. 1000ร piracetam potency. AMPA/NMDA modulation, BDNF increase.
DMAA (1,3-Dimethylamylamine) Guide
FDA banned CNS stimulant โ 25-75mg. Hemorrhagic stroke risk, cardiac events. Jack3d history.
DMHA (Octodrine) Guide
DMAA successor in pre-workouts. FDA warning letters issued. CNS stimulant โ 100-200mg.
Bacopa Monnieri Guide
Ayurvedic memory herb โ bacosides improve memory acquisition and reduce anxiety. Takes 8-12 weeks to work.
Alpha-GPC Guide
Most bioavailable choline source โ boosts acetylcholine, supports cognition, 14% power output increase in athletes.
Omega-3 & DHA Brain Health
DHA makes up 40% of brain PUFAs. VITALITY-BRAIN trial, MIDAS study, REDUCE-IT. Dosing for cognitive longevity and cardiovascular protection.
9-Me-BC: Dopamine Repair & Neuroprotection
ฮฒ-Carboline alkaloid โ upregulates TH, BDNF, GDNF, and 8+ neurotrophic factors in animal models. Dopamine restoration research chemical. MAO inhibitor. No human trials. Photosensitive.
๐ฌ Other Notable Compounds Research
Research on various peptides and compounds with unique mechanisms
Yohimbine Guide
Alpha-2 adrenergic antagonist for fasted stubborn-fat loss and ED โ narrow therapeutic window.
Vitamin B17 (Amygdalin/Laetrile)
Amygdalin / laetrile critical review: why it isn't a vitamin, cyanide toxicity, and the failed Mayo trial.
Propranolol (Inderal)
Non-selective beta blocker for performance anxiety, migraine, and tremor - plus PTSD memory research.
DIY mRNA Cancer Vaccine Pipeline
How personalized mRNA cancer vaccines are made in 8 steps, from tumor sequencing to the final syringe.
ACE-031 Guide
Myostatin/activin trap (ActRIIB-Fc). Phase 2 showed +1.7% lean mass in 29 days before bleeding halted trials.
AOD-9604 Research
HGH fragment (177-191) for fat loss. Stimulates lipolysis without IGF-1 effects. TGA approved in Australia.
Follistatin-344 Research
Myostatin inhibitor. Gene therapy research, "Schwarzenegger mice" with 2-3x muscle mass. Extremely expensive.
Melanotan II Research
Synthetic ฮฑ-MSH for UV-free tanning. Developed at U of Arizona. Precursor to PT-141. Side effects: nausea, flushing.
5-Amino-1MQ Research
NNMT inhibitor for fat loss. Very new โ only mouse data. Oral bioavailability. University of Texas research.
Ivermectin & Glioblastoma Research
Preclinical research on ivermectin's anti-glioblastoma effects โ Akt/mTOR inhibition, apoptosis pathways, and study limitations.
Joe Tippens Protocol
Alternative cancer protocol: fenbendazole, mebendazole, FECO, methylene blue, TUDCA, activated charcoal. Evidence review.
Makis Protocol
Dr. William Makis experimental cancer approach: ivermectin, fenbendazole, mebendazole dosing and supplements. Heavily disclaimed.
Telmisartan (Micardis) Guide
ARB with PPAR-ฮณ agonism โ blood pressure control plus metabolic benefits.
Nebivolol (Bystolic) Guide
Cardioselective beta blocker with NO-releasing vasodilation. Preferred for athletes.
Rosuvastatin (Crestor) Guide
Most potent statin โ reduces LDL 50-63%. JUPITER trial: 44% CV risk reduction.
Ezetimibe (Zetia) Guide
Cholesterol absorption inhibitor โ stacks with statins. IMPROVE-IT trial data.
Tesofensine Guide
Triple reuptake inhibitor โ 10-13% body weight loss in Phase 3. Not approved in US.
Adipotide (FTPP) Guide
Peptidomimetic targeting fat vasculature โ 11% weight loss in primates. Experimental.
Isotretinoin (Accutane) Guide
85% cure rate for severe acne. 0.5-1mg/kg/day x 15-20 weeks. iPLEDGE, liver monitoring.
Vitamin B12 Injectable Guide
Cyanocobalamin vs methylcobalamin, 1000mcg IM weekly protocol, bypasses GI absorption.
SNAP-8 (Acetyl Octapeptide-3) Guide
Cosmetic anti-wrinkle octapeptide that modulates SNARE complex to reduce expression lines up to 63%.
๐ Hair Loss Research Research
Evidence-based guides to hair loss treatments โ from FDA-approved options to research chemicals
Finasteride: DHT Blocker Research
FDA-approved 5ฮฑ-reductase inhibitor. Blocks DHT by 70%. 83% stop hair loss. Gold standard oral treatment since 1997.
Minoxidil: Hair Growth Research
FDA-approved vasodilator for hair growth. Topical and oral protocols. 40% responder rate. OTC since 1996.
RU-58841: Research Chemical
Experimental topical antiandrogen. NOT FDA-approved. Limited human data. Development abandoned 1990s. Use with caution.
๐งช Hormone Optimization Research
Evidence-based guides to hormone replacement therapy, TRT protocols, and endocrine optimization
Peptides & Fertility: The IVF Connection
The molecules in standard IVF protocols โ Lupron, hCG, kisspeptin, GH โ are the same as research peptides.
Testosterone & TRT: Complete Research Guide
Mechanisms, age-related decline data, FDA-approved formulations, dosing protocols, lab monitoring, side effects, and TRAVERSE trial safety data.
Gonadorelin: GnRH Analog for Fertility & TRT
Pulsatile GnRH analog that preserves HPTA on TRT. ~70% testosterone normalization. Fertility-preserving alternative to hCG.
Kisspeptin-10: Upstream GnRH Regulator
Emerging fertility treatment that stimulates LH pulses without receptor desensitization. IVF and hypogonadism applications.
Kisspeptin: Master GnRH Regulator & IVF Trigger
Deep research infographic on kisspeptin's HPG axis role, Imperial College IVF trials (~95% oocyte maturation, ~90% OHSS reduction), and fMRI brain studies.
Triptorelin: GnRH Agonist & PCT Reset
GnRH agonist for prostate cancer and controversial 'PCT reset' single-dose protocol. Initial LH surge then suppression.
HMG: Direct FSH/LH for Fertility
Human Menopausal Gonadotropin โ direct FSH/LH for hypogonadotropic hypogonadism and assisted reproduction.
Tamoxifen (Nolvadex): PCT SERM
Gold standard SERM for PCT. Raises LH 55%, restores testosterone in 75-85%. 20-40mg dosing protocols.
Raloxifene (Evista): Gyno Specialist
Best SERM for gynecomastia โ 86% response vs 41% tamoxifen. Bone-protective. 60mg daily.
Anastrozole (Arimidex): TRT AI
Most prescribed AI for TRT. Suppresses E2 80-90%. 0.5-1mg weekly. Reversible aromatase inhibitor.
Exemestane (Aromasin): Suicidal AI
Steroidal AI with irreversible binding. No E2 rebound. Better lipids. Take with fat.
Letrozole (Femara): Most Potent AI
99%+ E2 suppression. Off-label fertility use (first-line PCOS). Easy to crash estrogen.
Sildenafil (Viagra) Guide
PDE5 inhibitor โ FDA-approved for ED and PAH. 69% response rate at 50mg.
Finasteride (Propecia) Guide
5ฮฑ-reductase inhibitor โ blocks 65% of DHT. 83% maintain hair at 2 years.
๐งฌ Thyroid & Metabolic Research
Thyroid hormone replacement and metabolic optimization guides
L-Carnitine Injectable Guide
Injectable fatty-acid transporter โ near-100% bioavailability vs ~4-8% oral, plus ~25-30% muscle AR upregulation.
GC-1 (Sobetirome) Guide
Selective TRฮฒ thyromimetic that lowers LDL cholesterol without cardiac side effects; Phase I human data.
T4 (Levothyroxine) Guide
Most prescribed US drug. Prohormone converts to T3. Dosing 1.6mcg/kg. Brand vs generic debate.
T3 (Liothyronine) Guide
Active thyroid hormone. 4-5ร more potent than T4. Half-life ~1 day. Combination therapy debate.
Armour Thyroid (NDT)
Natural desiccated thyroid. Contains T4+T3+T2+T1+calcitonin. Patient preference vs synthetic.
๐ Longevity & Anti-Aging Protocols Protocols
Deep dives into high-profile longevity protocols and supplement stacks
FOXO4-DRI Guide
Senolytic D-retro-inverso peptide that clears senescent zombie cells by freeing p53 to trigger their apoptosis.
The Biohacker's Hierarchy
Foundation โ Optimization โ Advanced โ Experimental. The pyramid of what to do first and why.
10 Health Infrastructure Mistakes
The foundation most people skip before peptides: sleep, strength, cortisol, micronutrients. Ten mistakes โ and the fix for each.
Bryan Johnson Blueprint Protocol
Everything Johnson does to reverse aging, visualized. Biomarkers, supplements, sleep, exercise, and the science.
Bryan Johnson's Supplement Stack 2026
40+ supplements: exact doses, timing, purpose, and a budget-friendly starter stack.
Bryan Johnson's Sleep Protocol
8 months of perfect sleep scores. The resting heart rate method, 10 habits, and the published research behind it.
Rapamycin Longevity Guide
mTOR inhibitor extends lifespan in every organism tested. 25% mice lifespan increase. Weekly dosing.
Resveratrol Research
Sirtuin activator from red wine. David Sinclair's flagship compound. 70+ clinical trials.
Senolytics (Dasatinib + Quercetin)
Clearing zombie cells. Mayo Clinic research. Hit-and-run 3-day protocol.
Fisetin: Natural Senolytic
10x more potent than quercetin. Found in strawberries. Mayo Clinic AFFIRM trial.
Metformin for Longevity
Beyond diabetes. AMPK activator. TAME trial targeting aging as the root cause.
Natural Metformin Stack
Berberine, curcumin, cinnamon, ACV, and inositol โ the complete natural alternative with protocols and bloodwork.
Berberine Guide
Nature's metformin โ AMPK activation, blood sugar, lipids, dihydroberberine, and CYP3A4 drug interactions.
Curcumin Guide
Anti-inflammatory powerhouse โ NF-ฮบB inhibition, bioavailability forms compared, joint and metabolic health.
Apple Cider Vinegar Guide
Pre-meal blood sugar hack โ reduces post-meal glucose 20-35%. Dosing, dilution safety, forms compared.
Myo-Inositol Guide
Insulin sensitizer for PCOS and metabolic health โ the 40:1 ratio, fertility, anxiety, and dosing protocols.
๐ Practical Guides & How-Tos Guides
Step-by-step guides for beginners โ reconstitution, injection, storage, quality, and safety
Women's Peptide Protocols
Hormone-aware peptide framework for women: cycle-phase timing, dose reductions, and pregnancy contraindications.
Sleep Optimization Guide
Sleep protocol for peptide, GH, and TRT users: foundations, the Huberman stack, and DSIP/Epitalon peptides.
Peptide Genomics Guide
How genetic variants in CYP450, GH/GLP-1 receptors, and MTHFR shape your peptide response and dosing.
Omega-3 & DHA Guide
DHA is 40% of brain PUFAs; EPA fights inflammation. Dosing, rTG vs ethyl ester forms, and quality testing.
Nattokinase Guide
Fibrinolytic enzyme from fermented soy linked to a 36% arterial plaque reduction in a 1,062-person study.
Mebendazole (Vermox) Guide
FDA-approved antiparasitic (Vermox) being repurposed for cancer research with 50+ years of human safety data.
Talk to Your Doctor About Peptides
A framework for raising peptides with your doctor - what to say, what to bring, and when to find a specialist.
Fenbendazole Guide
Veterinary antiparasitic studied for anticancer activity: Dogra 2018 mechanisms, Joe Tippens protocol, dosing tiers.
FECO (RSO) Guide
High-THC whole-plant cannabis extract (Rick Simpson Oil): cannabinoid mechanisms, evidence, legal status.
Compounding Pharmacy Comparison
Compare top US compounding pharmacies for peptides and GLP-1s: 503A vs 503B, pricing, testing, red flags.
Activated Charcoal Guide
GI binder โ first-line for acute poisoning within 60 min, modest gas relief, but blocks meds within 2 hours.
Peptide FAQ
20 frequently asked questions answered โ basics, legality, reconstitution, side effects, specific compounds, sourcing, and costs.
Peptides for Beginners
Everything you need to know โ what peptides are, the 5 categories, legal status, and how to get started safely.
How to Reconstitute Peptides
Step-by-step guide to mixing peptides with BAC water. Ratios, math, common mistakes, and storage after mixing.
How to Inject Peptides
SubQ vs IM injection, needle gauge guide, site rotation diagram, pain management, and when to see a doctor.
Peptide Storage Guide
Temperature, light, shelf life by peptide. Lyophilized vs reconstituted storage, travel tips, and degradation signs.
Peptide Side Effects Guide
What's normal vs when to worry. Side effects by peptide category, GLP-1 nausea management, and red flags.
How to Verify Peptide Quality
Reading COAs, HPLC chromatograms, mass spec basics, red flags, Janoshik testing, and vendor evaluation checklist.
Complete Bloodwork Guide
What panels to order, when to test, and how to read results โ for peptides, SARMs, TRT, GLP-1s, and all biohacker compounds.
Bacteriostatic Water Guide
Peptide reconstitution essential. 0.9% benzyl alcohol preservative, 28-day multi-dose shelf life. Not the same as sterile water.
๐งฐ Interactive Tools Tools
Research tools to help you understand peptide stacking and regulatory status
Peptide Interaction Checker
Check compatibility for 15+ peptides. Timing recommendations, stacking scores, and popular pre-built stacks.
FDA Status Tracker
Track FDA approval status for 20 peptides. Pipeline visualization, trial phases, and key dates.
Stack Builder
Build your peptide stack with interaction warnings, dosing, and cycling recommendations.
๐ช SARMs & Performance Research
Selective Androgen Receptor Modulators โ clinical data, safety profiles, and regulatory status
Turkesterone Guide
Ecdysteroid from Ajuga turkestanica marketed as a natural anabolic via ERB, but human RCT evidence is weak.
Ostarine (MK-2866) Guide
Most researched SARM. Phase 2/3 trial data. 3% lean mass gain at 3mg. Mild suppression, 24hr half-life.
LGD-4033 (Ligandrol) Guide
1.21kg lean mass in 21 days at 1mg. Stronger than Ostarine, more suppressive. 36hr half-life.
RAD-140 (Testolone) Guide
Highest anabolic ratio (~90:1). Investigated for breast cancer. Neuroprotective in rodents.
Cardarine (GW-501516) Guide
NOT a SARM โ PPARฮด agonist. 68% endurance increase in mice. Cancer concern caused GSK to abandon.
YK-11 Guide
Dual mechanism: SARM + myostatin inhibitor. Only cell study data exists. Steroidal structure.
Follistatin-344 Deep Dive
Myostatin inhibitor โ removes muscle growth brake. Gene therapy 2x mass, peptide SubQ much less. Safety concerns.
S-23 Guide
Strongest SARM. Male contraceptive research: 100% reversible infertility in rats. Very suppressive.
PCT Complete Guide
Post-cycle therapy after SARMs. HPG axis recovery in 4-8 weeks. Enclomiphene vs Nolvadex vs Clomid protocols.
๐ Anabolic Steroids Harm Reduction
Educational harm-reduction guides for anabolic-androgenic steroids (AAS) โ mechanisms, risks, bloodwork, and PCT
TUDCA Guide
Bile acid liver protectant used with oral steroids and SARMs to cut ER stress and liver enzymes.
Methylstenbolone (M-Sten) Guide
Potent 17a-alkylated oral designer steroid, 660:90 ratio. Dry gains, extreme hepatotoxicity, banned under DASCA 2014.
Dianabol (Methandienone) Guide
17ฮฑ-alkylated oral AAS. 20-50mg/day. Anabolic:androgenic 90-210:40-60. Hepatotoxic. PCT required.
Turinabol (CDMT) Guide
East German Olympic doping drug. Oral, no aromatization. 20-50mg/day. Moderate liver toxicity.
Equipoise (Boldenone) Guide
Veterinary-origin injectable AAS. 300-600mg/week. Mild aromatization, increases RBC and appetite.
Halotestin (Fluoxymesterone) Guide
19ร anabolic, 8.5ร androgenic. Powerlifter pre-competition oral. Very hepatotoxic. 10-20mg/day.
Proviron (Mesterolone) Guide
Oral DHT derivative. Anti-estrogenic via SHBG binding. Enhances free testosterone. 25-75mg/day.
Masteron (Drostanolone) Guide
Injectable DHT derivative. Anti-estrogenic hardening agent. 300-500mg/week. No aromatization.
Winstrol (Stanozolol) Guide
FDA-approved for hereditary angioedema. Oral/injectable cutting AAS. No aromatization. Hepatotoxic.
Anavar (Oxandrolone) Guide
FDA-approved oral AAS. 20-80mg/day men, 2.5-10mg women. Anabolic:androgenic 322-630:24.
Primobolan (Methenolone) Guide
Very mild DHT-derivative AAS. 400-800mg/week injectable. Doesn't aromatize. Arnold's alleged favorite.
Anadrol (Oxymetholone) Guide
Most powerful oral AAS. 50-100mg/day. FDA-approved for anemia. Heavy hepatotoxicity, water retention.
Superdrol (Methasterone) Guide
Potent oral designer steroid. 10-20mg/day. Dry gains, extreme hepatotoxicity, banned by FDA 2012.
Nandrolone (Deca/NPP) Guide
FDA-approved for anemia. Joint relief, collagen synthesis, 200-600mg/week. 19-nor progesterone issues.
Trenbolone Guide
Most powerful injectable AAS. 5ร testosterone potency. Night sweats, tren cough, cardiovascular strain.
Trestolone (MENT) Guide
10ร more potent than testosterone. 19-nor, male contraceptive research. TRT alternative research.
DHB (Dihydroboldenone) Guide
5ฮฑ-reduced boldenone, no aromatization. Injectable 200-400mg/week. Very high PIP, dry gains.
Methylstenbolone (M-Sten) Guide
17ฮฑ-alkylated oral designer steroid banned under DASCA 2014. Hepatotoxicity, HPTA suppression.
DMZ (Dimethazine) Guide
Azine prodrug cleaving to methasterone in vivo. Extremely hepatotoxic oral designer steroid banned under DASCA 2014.
Clenbuterol Guide
ฮฒ2-adrenergic agonist for thermogenic fat loss. Not approved for humans in US. Cardiac risks, taurine depletion.
๐งซ More Research Recently Indexed
Liraglutide (Saxenda / Victoza)
The first daily GLP-1 receptor agonist โ SCALE Obesity, dosing, mechanism.
Exenatide (Byetta / Bydureon)
The original GLP-1 โ derived from Gila monster venom in 1992.
Cagrilintide & CagriSema
Long-acting amylin analog. REDEFINE 1 hit 20.4% weight loss with semaglutide.
Survodutide (BI 456906)
Boehringer's GLP-1/glucagon dual agonist โ 19% weight loss, 83% MASH improvement.
Orforglipron (Foundayo)
First oral GLP-1 pill, FDA-approved Apr 2026
Ozempic Face
Mechanism, prevention, and reversibility of GLP-1 facial volume loss
CagriSema
Novo Nordisk's cagrilintide + semaglutide combo
Mazdutide (IBI362)
Innovent's GLP-1/glucagon dual agonist โ phase 3 GLORY data
Danuglipron
Pfizer's discontinued oral GLP-1 โ why the program died
Oxytocin
Bonding peptide research โ intranasal, social cognition, replication issues
Ecnoglutide (XW003)
cAMP-biased GLP-1 โ Sciwind's phase-3 Lancet data
Ozempic Microdosing
0.05โ0.25 mg sub-therapeutic protocols and the evidence behind them
Klotho
The longevity protein โ 2026 human trials, AKL003 mRNA, Minicircle gene therapy
GLP-1 and Alcohol
How Ozempic cuts drinking โ JAMA Psychiatry RCT and 83K-patient cohort data
Larazotide (AT-1001)
Zonulin antagonist for celiac and Long COVID โ phase 2a 2026 readout
BPC-157 Capsules
Oral vs injectable BPC-157: bioavailability, capsule formats, what works
Wegovy vs Zepbound
2026 brand-by-brand comparison: cost, efficacy, coverage, who should pick what
GLP-1 and Thyroid Cancer
Black-box warning, rodent vs human evidence, MTC contraindication, real risk picture
Compounded Semaglutide 2026
Post-shortage legal status, FDA crackdown, Hims/Hers DOJ probe, your options
FDA July 2026 Peptide Hearing
PCAC reviews 7 peptides for the 503A bulks list โ full agenda and outcomes guide
BPC-157 for Dogs
Veterinary BPC-157: vet-supervised dosing, hip dysplasia, ACL recovery, IBD
Glow Blend (BPC + TB-500 + GHK-Cu)
The 3-peptide recovery + skin combo vial โ mechanism, dosing, vendor reality
HGH Pellets vs Reality
Why no HGH pellet exists, what works (Sogroya weekly, secretagogues), Testopel comparison
GLP-1 and Bone Density
Hip BMD loss data, tirzepatide HR 1.44, mitigation strategies for skeletal protection
Anxiety Peptide Stack
Selank + Oxytocin + DSIP intranasal โ mechanism, dosing, evidence reality check
Peptide PCT Decision Guide
When peptides need PCT vs cycling vs neither โ per-class breakdown
Peptides for Pets
Dogs, cats, horses: BPC-157, TB-500, oxytocin veterinary protocols
Myostatin Inhibitors
Bimagrumab, Trevogrumab, Apitegromab โ the post-GLP-1 muscle-preservation drug class.
GHK-Cu and BPC-157: Cancer Research
Preclinical gene-reset and VEGF-inhibition mechanisms for both peptides.
Muscle Is the Longevity Drug
Why rapamycin and metformin failed in humans, and what muscle does that drugs cannot.
The Avengers Stack
Six-peptide catastrophic-recovery protocol attributed to Jeremy Renner โ Tฮฑ1, BPC-157, MOTS-c, Thymalin, Semax, Selank.
Metabolic Adaptation: Why Reta Lets You Eat More
Why chronic dieters stall under 2,000 kcal and how retatrutide's glucagon arm may raise the metabolic ceiling.
Intermittent Fasting on GLP-1s
What the evidence actually shows about combining intermittent fasting with semaglutide, tirzepatide, and retatrutide โ risks, synergies, and the trials nobody has run.
Peptides 101: The 10 Categories
Infographic map of the 10 peptide categories โ every compound, every category, one guide.
Retatrutide Beyond Weight Loss
Brain, bone, testosterone & addiction effects of retatrutide โ the "soccer mom peptide" framing misses neuroprotection, synaptic preservation, bone formation, T support, and reward-circuit dampening.
Setmelanotide (Imcivree)
FDA-approved MC4R agonist for rare genetic obesity (POMC, LEPR, BBS) โ mechanism, trial data, and why it is not for general weight loss.
Melanotan I (Scenesse)
FDA-approved MC1R agonist for erythropoietic protoporphyria โ distinct from MT-II.
AHK-Cu Research
Hair-follicle copper peptide. VEGF upregulation, anagen extension. Distinct from GHK-Cu.
Cotadutide
Daily GLP-1/glucagon dual agonist โ mechanism, weight-loss & liver data.
Unlimited Energy Stack
SS-31 + MOTS-c + CJC/Ipamorelin + BPC-157 + TB-500 โ daily performance & recovery.
MOTS-c + NAD+ Stack
Focused 2-compound cellular-energy protocol โ mitochondrial biogenesis ร sirtuin fuel.
Adamax
Adamantane-modified N-acetyl Semax research peptide โ Semax science vs unstudied claims.
Thymalin
Thymus polypeptide complex (KE + EW dipeptides) studied for T-cell maturation, immunity, and geroprotection.
Thymulin
Zinc-bound thymic nonapeptide hormone (FTS). T-cell maturation and anti-inflammatory effects in rodent models.
Skin Aging Stack
7-compound protocol โ GHK-Cu, GLOW, NAD+, Vilon, Regeno, Thymalin, Epitalon. Topical + oral + SC lanes.
FLGR242
Vendor-marketed Follistatin variant with albumin-binder. Zero peer-reviewed studies โ honest review.
Peptide Therapy Monitoring
The full process of monitoring peptide therapy safely โ providers, baseline labs, tracking, and cadence.
Best Compounds for Blood Flow
Evidence-ranked guide to PDE5 inhibitors, L-citrulline, dietary nitrate, and BPC-157 for blood flow and endothelial health.
Oral Astaxanthin & Skin Aging
What the controlled-trial evidence actually shows for oral astaxanthin and aging skin โ elasticity and moisture yes, wrinkle reversal no.
Cardiovascular & Endothelial Health
Residual-inflammation cardiology framing applied to GLP-1 agonists, BPC-157, PDE5 inhibitors and omega-3s.
Retatrutide: Cholesterol, BP & Joint Health
Beyond weight loss โ what reta's trials show for lipids, blood pressure, glycemia and the pending knee-OA/sleep program.
Lactoferrin for Fat Loss
A milk glycoprotein studied for visceral fat loss โ the honest evidence behind one small 2010 RCT.
Focus Stack
A calm-alert adult cognitive stack: creatine, magnesium L-threonate, L-theanine and taurine.
Skin Care Stack
A 5-step holistic skin protocol: tretinoin, sun protection, microneedling/lasers, red light therapy and GHK-Cu.
Is BPC-157 Banned by WADA?
BPC-157's WADA S0 status and whether anti-doping labs can detect it.
Peptide Injection-Site Reactions
Why peptide shots cause itching, redness, and welts โ the mast-cell histamine (MRGPRX2) mechanism, not a bad batch.
Swiss Chems Review
Honest vendor review: the Dec 2024 FDA warning letter, COAs, card + crypto checkout, and our affiliate disclosure.
SLU-PP-915: Oral Exercise Mimetic
Orally bioavailable pan-ERR agonist and next-gen analog of SLU-PP-332. How they differ, preclinical data, and the zero-human-data gate.
Vesugen (KED)
The KED vascular bioregulator peptide โ endothelial claims vs the actual PubMed evidence.
How to Vet a Compounding Pharmacy
The six objective checks โ state license, PCAB, NABP .pharmacy, LegitScript, FDA records, 503A vs 503B โ you can run yourself.
FDA Approval Tracker
Which peptides are FDA approved, in trials, or research chemicals โ sourced & dated
GLP-1 & Fatty Liver Mechanism
How semaglutide improves MASH partly independent of weight loss โ via liver vessel-lining GLP-1 receptors.
GLP-1, Smell & Taste
A 2026 JAMA cohort on GLP-1 drugs and smell/taste changes โ signal, mechanism, and the real risk.
Obesity Drugs Ranked
19 weight-loss drugs ranked by real one-year data from a 262-trial BMJ meta-analysis.
Retatrutide, Mood & Focus
Does retatrutide affect anxiety, focus and dopamine? The reward-circuit evidence vs the viral anecdotes.
Dopamine Focus Stack
Bromantane, NALT, DLPA, Vilon and circadian light โ a dopamine-plus-endorphin stack, graded honestly.
DL-Phenylalanine (DLPA)
The racemic amino acid feeding dopamine synthesis and inhibiting enkephalinase โ mechanism and caveats.
Tesamorelin
GHRH analog that cuts visceral fat 15% - evidence vs the viral muscle & longevity hype.
Mexidol
Called an S-tier nootropic online. Every controlled trial is in stroke patients โ here is what the evidence actually shows.
SANA (MVD1)
Salicylate nitroalkene that drives creatine-dependent fat thermogenesis โ Phase 1 data, examined.
Food Noise & Reta-Cag
What food noise is, and the honest evidence behind the retatrutide+cagrilintide stack people use for it.
ATX-304 / O-304
The pan-AMPK activator hyped as โthe next retatrutideโ โ what one human trial actually showed vs mouse data.
Pinealon & Sleep
Does the Glu-Asp-Arg peptide really boost REM? The viral sleep-tracker claim vs. the published evidence.
Pemvidutide (ALT-801)
Altimmune's GLP-1/glucagon dual agonist โ muscle-sparing Phase 2 obesity and MASH data.
NVG-291
NervGenโs ISP/PTPฯ nerve-regeneration peptide โ real preclinical evidence vs. viral human hype.
Retatrutide
The GIP/GLP-1/glucagon triple agonist โ peer-reviewed phase 2 trial data and real TRIUMPH phase 3 status.
Retatrutide + Tirzepatide Stacking
What the phase 2 evidence says about combining the two GLP-1 drugs.
Tesamorelin + Ipamorelin
The dual-receptor GH stack โ GHRH analog + ghrelin mimetic, and what the evidence actually shows.
Eloralintide
Investigational non-GLP-1 amylin agonist โ up to ~20% weight loss in Phase 2.
Best Peptides for Muscle & Performance
Tiered, evidence-first guide to muscle & performance compounds โ recovery peptides, GH-axis secretagogues, and anabolic SARMs, each with WADA status.
VK2735
Viking Therapeutics' dual GIP/GLP-1 agonist โ VENTURE Phase 2 data, and the Zealand Pharma oral-drug myth.
Mastic Gum + BPC-157 for H. Pylori
Does the viral mastic gum + oral BPC-157 gut-repair stack hold up? An evidence review.
N-Acetyl Glucosamine (NAG)
The amino sugar behind mucins, cartilage and N-glycans โ and why it is not NAC.
NAD+ Therapy: Hype vs. Evidence
Is NAD+ really 'peptide therapy'? What human trials show about NAD+, sermorelin and glutathione.
SLU-PP-332 & SLU-PP-915
Synthetic ERR "exercise mimetics" โ what the mouse data shows and why there is no human evidence.
GLP-1, Dopamine & Anhedonia
Does GLP-1 blunt the brainโs dopamine โwantingโ system? What the reward-circuit evidence actually shows.
Retatrutide & Heart Rate
Does retatrutide raise resting heart rate and blunt HRV? What the trials actually show vs. the viral claims.
๐งญ Explore the Full Library Navigation
Compound monographs, dosage calculators, and reference hubs across HighPeptides.
Compound Monographs
All Compound Monographs
Browse the full index of peptide and compound reference pages.
Tributyrin
Butyrate prodrug studied for gut-barrier and metabolic support.
Vladonix
Thymus bioregulator peptide โ immune and geroprotective research.
Zinc L-Carnosine
Zinc-carnosine complex studied for gastric-mucosa protection.
Larazotide
Tight-junction regulator investigated for intestinal permeability.
Palmitoylethanolamide (PEA)
Endogenous fatty-acid amide studied for pain and inflammation.
Sigumir
Cartilage bioregulator peptide from the Khavinson series.
Thymagen
Thymus-derived bioregulator studied for immune modulation.
Cartalax
AED tripeptide bioregulator researched for connective tissue.
Dosage Calculators
Peptide Dosage Calculator
Reconstitution and dosing math for any peptide.
PT-141 Calculator
Dose and reconstitution helper for PT-141 (bremelanotide).
Semaglutide Calculator
Unit and dose conversions for semaglutide titration.
CJC-1295 / Ipamorelin Calculator
Combined dosing math for the CJC-1295 + Ipamorelin stack.
GHK-Cu Calculator
Reconstitution and dose helper for GHK-Cu.