HGH Fragment • TGA Approved (Australia)

AOD-9604: The Fat Loss Fragment

By , HighPeptides Editor

Last updated: March 2026

AOD-9604 is a synthetic peptide corresponding to amino acids 177–191 of human growth hormone — the C-terminal fragment responsible for fat metabolism. Unlike full HGH, it stimulates lipolysis and inhibits lipogenesis without affecting IGF-1 levels or blood glucose. Research dosing is typically 500 mcg via subcutaneous injection. Approved as a supplement by Australia's TGA; not FDA-approved.

0
Research Dose
(typical/day)
0
HGH Amino
Acids
0
Approved
(Australia)
📋 On this page
  1. What Is AOD-9604?
  2. What the Research Shows
  3. Key Takeaways
  4. 🔬 Verified Research Source
  5. 🛒 Recommended Products
  6. 🔗 Related Resources
Background

What Is AOD-9604?

AOD-9604 is a synthetic peptide corresponding to amino acids 177-191 of the growth hormone sequence — the C-terminal fragment responsible for fat metabolism, isolated from the growth-promoting effects.

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Stimulates Lipolysis

AOD-9604 directly stimulates the breakdown of stored fat (lipolysis) in adipose tissue, promoting fat loss without affecting lean muscle.

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No IGF-1 Effect

Unlike full HGH, AOD-9604 does not affect IGF-1 levels or blood glucose. This avoids the metabolic side effects associated with growth hormone.

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Inhibits Lipogenesis

AOD-9604 also inhibits the creation of new fat cells (lipogenesis), helping prevent fat accumulation during use.

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Subcutaneous Delivery

Administered via subcutaneous injection. The peptide is stable and has a good safety profile in research models.

Research

What the Research Shows

Research data on AOD-9604's fat loss mechanism.

📋 Regulatory Status TGA Approved Research Only (US)

AOD-9604 is approved as a supplement in Australia (TGA) but is not FDA approved in the United States. Limited clinical trial data exists.

Lipolysis Stimulation
Direct fat breakdown in adipocytes
Significant
IGF-1 Independence
Does not affect IGF-1 or blood glucose
Confirmed
Weight Loss (Animal Studies)
Reduced body fat in obese rodent models
Demonstrated
Bottom Line

Key Takeaways

✅ What We Know
  • HGH fragment (amino acids 177-191)
  • Stimulates lipolysis directly
  • Does not affect IGF-1 or blood glucose
  • Approved as supplement in Australia (TGA)
  • No growth effects like full HGH
⚠️ What We Don't Know
  • Limited human clinical trial data
  • Not FDA approved in US
  • Optimal dosing protocols not established
  • Long-term safety unknown

🔬 Verified Research Source

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⚠️ Important Disclaimer

This page is for educational purposes only. AOD-9604 is not FDA approved. TGA approval is for Australia only. Always consult a healthcare provider.